How to Start a Pharmaceutical Business in France as a Foreigner?

Imagine stepping into a market worth over €58 billion and growing. That’s the scale of France’s pharmaceutical industry—a powerhouse in Europe’s healthcare sector. With a strategic location at the heart of Europe, robust government support, and a world-class workforce, France offers unparalleled opportunities for entrepreneurs in the pharmaceutical space.

Why France, you ask? This country is home to some of the largest pharmaceutical companies globally, like Sanofi and Ipsen, driving innovation in medicine and healthcare. Combine that with tax incentives and access to cutting-edge R&D facilities, and you have a winning formula. 

But you must be wondering how can I start a pharmaceutical business in France. If yes, then this guide is for you. It will cover all the necessary steps from selecting the best legal structure to covering the process and leading pharma companies, we’ve got you covered. 

Connect with our industry experts to establish yourself in one of the most profitable markets in the world. Let’s get started!

Why Start a Pharmaceutical Business in France?

France’s pharmaceutical market ranks as one of the largest in Europe, contributing significantly to the global healthcare industry.

Here’s why:

• Strategic Location: France’s central location in Europe makes it simple to reach the 448 million consumers in the EU.
• Global Leader in Pharmaceuticals: France is the 5th-largest pharmaceutical market in the world and the 2nd-largest in Europe, contributing significantly to global health innovations. In 2023, the French pharmaceutical market was valued at over EUR 60 billion, with exports accounting for EUR 33 billion, reflecting its robust international trade.
• Highly Skilled Workforce: Over 100,000 professionals work in the pharmaceutical and biotech industries, ensuring access to top talent.
• Strong R&D Presence: France invests heavily in research and development, with over €5 billion allocated annually to pharmaceutical R&D efforts.

Process of Registering a Pharmaceutical Company in France

Registering a pharmaceutical business in France involves these streamlined steps:

Step 1: Choose the Right Business Structure 

Decide on a legal entity, such as SARL, SAS, or SA, depending on your operational and funding needs. The SAS is often preferred by foreign investors for its flexibility and limited liability.

Step 2: Prepare Necessary Documents: 

Gather the required documents, including articles of association, proof of identity and address, a detailed business plan, and the certificate of deposit for your initial capital in a French bank account.

Step 3: File with the Trade Register: 

Submit your application to the Trade and Companies Register (RCS) via the Centre de Formalités des Entreprises (CFE). This step legally establishes your company in France.

Step 4: Register for Taxes: 

Obtain your VAT number and register with the local tax authorities to ensure compliance with French tax regulations.

Step 5: Obtain Regulatory Licenses: 

Apply for mandatory licenses from the French National Agency for Medicines and Health Products Safety (ANSM) to manufacture, import, or market pharmaceuticals.

Once these steps are completed, your pharmaceutical business is officially registered and ready to operate within France’s regulatory framework.

Documents Required to Register a Pharmaceutical Company in France

The documentation required to start a pharmaceutical business in France includes:

• Proof of Identity: Passport or national ID of the business owners.
• Business Plan: A detailed document that includes your financial estimates, market analysis, and business goals.
• Articles of Association: Defines the firm’s structure and governance.
• License Application: Application forms for manufacturing or distribution authorization.
• Tax Registration Number (SIRET): Issued after registering with the French Chamber of Commerce.

Best Business Structure to Start a Pharmaceutical Business in France

Selecting the right business structure is pivotal for success and operational efficiency.

Here are the top options available to set up a pharma business in France for entrepreneurs:

1. Société à Responsabilité Limitée (SARL)

This structure is perfect for small and medium-sized enterprises with limited liability protection for shareholders. It is straightforward to establish and has lower compliance costs, but it can be less flexible when transferring shares or bringing in new investors.

2. Société par Actions Simplifiée (SAS)

SAS in France offers unmatched flexibility in governance, making it a favourite among startups and foreign investors. It provides limited liability protection and allows easy adaptation to changing business needs, but it requires slightly higher administrative management compared to SARL.

3. Société Anonyme (SA)

Designed for larger enterprises, the SA is suitable for businesses planning to raise significant capital or go public. While it provides access to public funding and extensive operational capabilities, the initial setup and ongoing compliance requirements are more demanding.

For most entrepreneurs in the pharmaceutical sector, the SAS is often the optimal choice due to its balance of flexibility, scalability, and legal protection.

Leading Pharmaceutical Companies in France

France hosts some of the world’s most prominent pharmaceutical companies:

• Sanofi: One of the top 10 global pharmaceutical companies, generating €39 billion in 2023.
• Ipsen: Specializing in oncology, neurology, and rare diseases.
• Servier: A leading player in cardiology and diabetes medications.
• Pierre Fabre: Renowned for dermatology and consumer healthcare products.